Structure of the policy recommendation

Adhere to the rubric,

1. You can start the recommendation as such:

Attention – Parliamentary Committee for Health and Emerging Biotechnology

Policy recommendation on clinical implementation of mitochondrial replacement therapy.

2. Briefly identify, define and clarify the technique of mitochondrial donation / replacement

3. Identify and discuss the key safety issues that your expert panel consulted on (i.e. analysis), or that you consider salient to
the technique of mitochondrial replacement – use evidence from the primary literature, and evidence gained during the debate
(e.g. results of polls). Provide a balanced appraisal of each issue

a. Provide explicit recommendation on how the government should proceed, in terms If introduction of policy to legislate
mitochondrial replacement in Australia. Base your recommendations on the analysis ofthe key issues. Do any ofthe identified
issues represent significant risk in terms of implementing this technique into the clinic? If so, how can these concerns be
resolved, and/or risks mitigated?

Is the technique ready for processes to initiate that lead up to legislation in Australia, is further research required, and ifso,
detail the types of experiments required, or should the technique be dismissed based on the evidence already available.