Order Description

Investigate the stoichiometry and pH stability of iron complexes with potential therapeutic effects and their chemical significance. The potential therapeutic iron chelators maltol, kojic acid,
2,3-dihydroxypyridine and current iron chelator deferiprone will be investigated. Another aim is to investigate the use of these potential iron chelators as a form of therapy with the use of a
solid support medium in the form of silica gel and assess its stability under various pHs.

Materials:
1000 mL, 250 mL and 100 mL conical flasks
Test tubes
25 mL and 5 mL pipettes
Beakers and thermometer
Test tube rack
Genysis 6 spectrophotometer
Plastic UV cell
Diskette
Pasteur pipettes
Chemicals:
Maltol (3-Hydroxy-2-methyl-4H-pyran-4-one)
Kojic Acid (5-Hydroxy-2-(hyroxymethyl)-4H-pyran-4-one)
2,3-Dihydroxypyridine
Deferiprone (3-Hydroxy-1,2-dimethylpyridin-4(1H)-one)
Morpholine
Piperidine