Risk of Developing Venous Thromboembolism in Immobilized Patients

Order Description
The name of my research project is Risk of Developing Venous Thromboembolism in Immobilized Patients.

My PICO question for the project is

PICO question: In immobilized patient who is at risk for developing venous thromboembolism, how does pharmacological prophylaxis (antiplatelet agents) compared to
mechanical prophylaxis (intermittent compression devices) affect the development of venous thromboembolism within 1 week of treatment?

You have to choose any 4 article from the list provided below:

– Frontera, J. A., Jovine, M., Hunter, S., Catalano, A., & Gordon, E. (2014). Comparison of Pharmacologic versus Mechanical Venous Thromboemoblism Prophylaxis in
Patients with Intracranial Hemorrhage. Stroke, 45(Supp.1).

– Gaspard, D., Vito, K., Gerber, D. (2015). Comparison of Chemical and Mechanical Prophylaxis of Venous Thromboembolism in Nonsurgical Mechanically Ventilated
Patients. Thrombosis, 2015: 1 – 6.

– Gharabaghi, M. & Meshkini, A. (2015). A Comparison of pharmacologic and mechanical prophylaxis on the prevention of deep vein thrombosis in spinal cord injury.
Trauma monthly, 20(Special Issue): e28508.

– Holwell, A., McKenzia, J., Holmes, M., Woods, R., Nandurkar, H., Tam, C. S., & Bazargan, A. (2014). Venous thromboembolism prevention in patients undergoing
colorectal surgery for cancer. ANZ Journal of Surgery, 84, 284-288.

– Phillips, N. M. & Heazlewood, V. J. (2012). Venous thromboembolism prophylaxis audit in two Queensland hospitals. International Medicine Journal, 43(5), 560-6. Doi:
10.1111/imj.12033.

– Pontelli, E., Scialom, J., Dos, T. & Pontelli2, S. (2012). Pharmacologic and intermittent pneumatic compression thromboembolic prophylaxis in 563 consecutive
abdominoplasty cases. Revista Brasileira de Cirurgia Plástica, 27(1): 77 – 86.

– Sobieraj-Teague, S., Hirsh, J., Yip, G……..Eikelboom, J. (2012). Randomized controlled trial of a new portable calf compression device (Venowave) for prevention of
venous thrombosis in high-risk neurosurgical patients. Journal of Thrombosis and Haemostasis, 10(2): 229 – 235.

– Yamamoto, T., Nakamura, M., Kuroiwa, M., & Tanaka, K. (2013). Current prevention practices for venous thromboembolism in Japanese intensive care units. Journal of
Anesthesia, 27, 931-934. Doi: 10.1007/s00540-013-1626-4.

1. Describe similarities in research methods across the four studies.
2. Describe differences in research methods across the four studies.
3. Discuss the practical or clinical significance of the findings to the evidence-based practice of nursing.
4. Provide an answer to the PICO question, or describe why you are not able to definitively answer the question.
5. References should include 4 articles you have picked and 1 more additional reference you allowed if you need to use to describe similarities and differences of
research methods. (number of sources 4-5)