Grey-scale Median (gsm) And Other Predictors Of Successful Sclerothrombus Aspiration Following Foam Sclerotherapy

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This must be written like a manuscript you would submit for a medical journal. The manuscript must be written based on the following abstract:

Objective(s): Foam sclerotherapy is often associated with the formation of a tender and painful sclerothrombus. Drainage of this thrombus improves overall symptoms but
it requires painful needle aspirations. These aspirations can fail to drain the sclerothrombus in up to 50% of the patients even when one awaits the recommended 3-5
weeks post-sclerotherapy. To improve the success rate of needle aspiration we analyzed the role of sclerothrombus GSM and other potential predictors including vein
diameter and timing of aspiration.
Methods: Thirthy-five symptomatic patients (27 females; 8 males) with mean age 51.5 years±13.7) underwent 47 duplex guided sclerothrombus aspiration procedures between
13 and 114 days (mean 43 days ±21.5) after foam sclerotherapy over a 5 months period. Using B-mode duplex images, we measured vein diameters (1.6mm to 12 mm, mean
4.6±2 mm) and quantified sclerothrombus GSM (Photoshop®) for 120 target venous segments (13 to 38, mean 25.7±4.8).
Results: Complete aspiration of sclerothrombus occurred in 83 segments (69%, Group I), partial aspiration in 22 cases (18%, Group II) and failed aspiration in 15 cases
(13%, Group III).
The mean GSM for Group I was 24.2 ± 4 and it was significantly lower as compared to the one obtained for Group II (29 ± 4.4, p<0.0001) and Group III (29.8 ± 5.9,
p<0.0001).
Mean diameter of the drained veins in Group I (4.1 ± 1.7 mm) was significantly smaller as compared to Group II (5.2 ± 2.3 mm, p=0.03) and Group III (6.5 ± 2 mm,
p<0.0001).
However, there was no statistically significant difference in the mean interval time from sclerotherapy to needle aspiration among the 3 groups. It was 41.5 ± 21.8
days for Group I as compared to Group II (51.3 ± 19.6 days, p = 0.06) and Group III (42.5 ± 21 days, p=0.87).

Conclusions: These data show that GSM of the sclerothrombus and vein diameter are reliable predictors of successful aspiration. Contrary to previous belief the time
interval between foam sclerotherapy and sclerothrombus aspiration was not a significant indicator of successful aspiration.

The resources you must use to write the paper have to be based off anything on gray scale median, there is not much information on gray scale median and sclerotherapy
but you must find what you can and also use articles such as ones from here:

https://www.google.com/#q=gray+scale+median+

Using these articles and the abstract a manuscript must be written that would look like it can be submitted to a medical journal. I will attach 3 files that explain
how to do this. The discussion section of this paper should be about what GSM is, how its used, how did people in abstract use it, how it is applied in other fields,
how it is applied in sclerotherapy, how can this be useful in medicine, etc etc.